Article
PKCdelta mediates testosterone-induced increases in coronary smooth muscle Cav1.2.
The Journal of biological chemistry - 30 Dec 2005
Maddali Kamala K, Korzick Donna H, Tharp Darla L, Bowles Douglas K
Abstract excerpt
Sex hormones have emerged as important modulators of cardiovascular physiology and pathophysiology. Our previous studies demonstrated that testosterone increases expression and activity of L-type, voltage-gated calcium channels (Cav1.2) in coronary arteries of males. The purpose of the present study was to determine whether testosterone (T) alters coronary protein kinase C delta (PKCdelta) expression and whether...
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