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Gonadal sex determination in vertebrates: rethinking established mechanisms

15 Mar 2025

Abstract excerpt

Sex determination and differentiation are fundamental processes that are not only essential for fertility but also influence the development of many other organs, and hence, are important for species diversity and survival. In mammals, sex is determined by the inheritance of an X or a Y chromosome from the father. The Y chromosome harbours the testis-determining gene SRY, and it has long been thought that its...

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PMID: 40162719
DOI: 10.1242/dev.204592

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