Article
Induction of the reelin promoter by retinoic acid is mediated by Sp1.
Journal of neurochemistry - 1 Oct 2007
Chen Ying, Kundakovic Marija, Agis-Balboa Roberto C, Pinna Graziano, Grayson Dennis R
Abstract excerpt
We have previously described the cloning of the human reelin promoter and provided evidence that it is regulated, in part, through changes in methylation. Results from our current studies provide a more detailed analysis of this promoter and the interactions of the transcription factors Sp1 and paired box gene 6 (Pax6) with their recognition sites. The promoter was studied in NT2 cells which are a neuroprogenitor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
