Article
Presence of lipoprotein lipase S447X stop codon affects the magnitude of interleukin 8 release after cardiac surgery with cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery - 1 Aug 2007
Ak Koray, Isbir Selim, Tekeli Atike, Ergen Arzu, Atalan Nazan, Dogan Selami, Civelek Ali, Arsan Sinan
Abstract excerpt
OBJECTIVE: Current data suggest that individual genetic predisposition may influence the magnitude of cytokine response and the degree of organ dysfunction after cardiopulmonary bypass. Lipoprotein lipase S447X polymorphism has been shown to be protective against atherosclerosis. The aim of the study was to investigate the effect of lipoprotein lipase S447X polymorphism on cytokine release and early outcome after...
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