Article
Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2001
Brull D J, Montgomery H E, Sanders J, Dhamrait S, Luong L, Rumley A, Lowe G D, Humphries S E
Abstract excerpt
Interleukin-6 (IL-6) synthesized in response to diverse stimuli may play an important role in bridging the inflammatory and atherosclerotic processes. The acute-phase response after coronary artery bypass graft surgery (CABG) is associated with the induction and release of cytokines, such as IL-6...
Topics
- Coronary Artery Bypass
- Coronary Artery Disease
- Female
- Forecasting
- Gene Frequency
- Genetic Markers
- Humans
- Inflammation
- Interleukin-6
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic