Article
Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2001
Brull D J, Montgomery H E, Sanders J, Dhamrait S, Luong L, Rumley A, Lowe G D, Humphries S E
Abstract excerpt
Interleukin-6 (IL-6) synthesized in response to diverse stimuli may play an important role in bridging the inflammatory and atherosclerotic processes. The acute-phase response after coronary artery bypass graft surgery (CABG) is associated with the induction and release of cytokines, such as IL-6. We have examined the effect of common polymorphisms in the IL-6 gene promoter (-174G>C, -572G>C, and -597G>A) on IL-6...
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