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Article

The voltage dependent anion channel affects mitochondrial cholesterol distribution and function.

Archives of biochemistry and biophysics - 15 Oct 2007

Campbell Andrew M, Chan Samuel H P

Abstract excerpt

We have observed abnormally high membrane cholesterol levels and a subsequent deficiency of oxidative energy production in mitochondria from cultured Morris hepatoma cells (MH7777). Using cholesterol affinity chromatography and MALDI-TOF Mass Spectrometry, we have identified the voltage dependent anion channel (VDAC) as a necessary component of a protein complex involved in mitochondrial membrane cholesterol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potential, Mitochondrial

Share to Mitochondria, Liver

Share to Oxidative Phosphorylation

Share to Rats, Sprague-Dawley

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 17662230
DOI: 10.1016/j.abb.2007.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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