Article
Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention.
Biochimica et biophysica acta - 10 Sept 2002
Pedersen Peter L, Mathupala Saroj, Rempel Annette, Geschwind J F, Ko Young Hee
Abstract excerpt
Despite more than 75 years of research by some of the greatest scientists in the world to conquer cancer, the clear winner is still cancer. This is reflected particularly by liver cancer that worldwide ranks fourth in terms of mortality with survival rates of no more than 3-5%. Significantly, one of the earliest discovered hallmarks of cancer had its roots in Bioenergetics as many tumors were found in the 1920s...
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