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Article

Propylene oxide: genotoxicity profile of a rodent nasal carcinogen.

Critical reviews in toxicology - 1 Jan 2007

Albertini Richard J, Sweeney Lisa M

Abstract excerpt

Propylene oxide (PO) is a DNA-reactive genotoxic agent; that is, it reacts with DNA to produce lesions in the genetic material. PO also induces tumors in rodents, although only at high concentrations and at portals of entry. This review of PO's genotoxicity profile is organized according to endpoints measured, that is, nonmutational or mutational endpoints, and as to whether the results were from in vitro or in...

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PMID: 17661214
DOI: 10.1080/10408440701382959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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