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Article

Genotoxic effects of ethylene oxide, propylene oxide and epichlorohydrin in humans: update review (1990-2001).

Mutation research - 1 Dec 2002

Kolman Ada, Chovanec Miroslav, Osterman-Golkar Siv

Abstract excerpt

Ethylene oxide (EtO), propylene oxide (PO) and epichlorohydrin (ECH) are important industrial chemicals widely used as intermediates for various synthetic products. EtO and PO are also environmental pollutants. In this review we summarize data published during the period 1990-2001 concerning both the genotoxic and carcinogenic effects of these epoxides in humans. The use of DNA and hemoglobin adducts as...

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PMID: 12464351
DOI: 10.1016/s1383-5742(02)00067-4

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