Analysis of genotoxicity and the carcinogenic mode of action for ortho-phenylphenol.

doi:10.1002/em.20116

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Article

Analysis of genotoxicity and the carcinogenic mode of action for ortho-phenylphenol.

Environmental and molecular mutagenesis - 1 Jun 2005

Brusick David

Abstract excerpt

Ortho-phenylphenol (OPP) and its sodium salt (SOPP) are commercial products that have wide human exposure and have been shown in several studies to be rodent carcinogens. Genetic toxicology data were assessed in an attempt to understand the carcinogenic mode of action of OPP and SOPP. More than 130 studies were evaluated to determine if OPP, SOPP, or any of their enzymatic or nonenzymatic breakdown products react...

Topics

Benzoquinones
Biphenyl Compounds
Carcinogenicity Tests
DNA
DNA Adducts
DNA Damage
Databases, Factual
Hydroquinones
Mutagenicity Tests
Mutagens
Mutation
Toxicity Tests

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Open in PubMed

Identifiers

PMID: 15714474
DOI: 10.1002/em.20116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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