Article
Evaluation of propylene oxide for mutagenic activity in 3 in vivo test systems.
Mutation research - 1 Jan 2000
Hardin B D, Schuler R L, McGinnis P M, Niemeier R W, Smith R J
Abstract excerpt
Propylene oxide (CAS No. 75-56-9) was tested for mutagenic activity following vapor exposure using 3 in vivo test systems. Rat dominant lethal and mouse sperm-head morphology assays were conducted using males exposed to propylene oxide at 300 ppm in a dynamic exposure chamber for 7 h per day on 5 consecutive days. A sex-linked recessive lethal test in Drosophila melanogaster employed a 24-h static exposure to...
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