Article
Association of genetic polymorphisms of N-acetyltransferase 2 and susceptibility to esophageal cancer in north Indian population.
Cancer investigation - 1 Aug 2007
Jain Meenu, Kumar Shaleen, Lal Puneeta, Tiwari Anu, Ghoshal U C, Mittal Balraj
Abstract excerpt
Esophageal cancer is multifactorial disease involving environmental and genetic risk factors. Tobacco smoke and alcohol are strong environmental risk factors. N-acetyltransferase 2 (NAT2) is known to metabolize heterocyclic amine carcinogens in tobacco smoke. The purpose of this study was to dete...
Topics
- Adenocarcinoma
- Arylamine N-Acetyltransferase
- Carcinoma, Squamous Cell
- Environment
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genotype
- Humans
- India
- Lymphatic Metastasis
- Occupational Exposure
- Polymorphism, Genetic
- Risk Factors
- Smoking