Article
Association of genetic polymorphisms of N-acetyltransferase 2 and susceptibility to esophageal cancer in north Indian population.
Cancer investigation - 1 Aug 2007
Jain Meenu, Kumar Shaleen, Lal Puneeta, Tiwari Anu, Ghoshal U C, Mittal Balraj
Abstract excerpt
Esophageal cancer is multifactorial disease involving environmental and genetic risk factors. Tobacco smoke and alcohol are strong environmental risk factors. N-acetyltransferase 2 (NAT2) is known to metabolize heterocyclic amine carcinogens in tobacco smoke. The purpose of this study was to determine whether genetic polymorphism in the NAT2 and their interaction with environmental factors influence the...
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