Article
Reduced levels of Su(var)3-9 but not Su(var)2-5 (HP1) counteract the effects on chromatin structure and viability in loss-of-function mutants of the JIL-1 histone H3S10 kinase.
Genetics - 1 Sept 2007
Deng Huai, Bao Xiaomin, Zhang Weiguo, Girton Jack, Johansen Jørgen, Johansen Kristen M
Abstract excerpt
It has recently been demonstrated that activity of the essential JIL-1 histone H3S10 kinase is a major regulator of chromatin structure and that it functions to maintain euchromatic domains while counteracting heterochromatization and gene silencing. In the absence of JIL-1 kinase activity, the m...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.