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Article

Heterochromatin protein 1 is required for the normal expression of two heterochromatin genes in Drosophila.

Genetics - 1 Jun 2000

Lu B Y, Emtage P C, Duyf B J, Hilliker A J, Eissenberg J C

Abstract excerpt

The Su(var)2-5 locus, an essential gene in Drosophila, encodes the heterochromatin-associated protein HP1. Here, we show that the Su(var)2-5 lethal period is late third instar. Maternal HP1 is still detectable in first instar larvae, but disappears by third instar, suggesting that developmentally late lethality is probably the result of depletion of maternal protein. We demonstrate that heterochromatic silencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10835392
DOI: 10.1093/genetics/155.2.699
PMCID: PMC1461102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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