Article
The JIL-1 kinase regulates the structure of Drosophila polytene chromosomes.
Chromosoma - 1 Aug 2005
Deng Huai, Zhang Weiguo, Bao Xiaomin, Martin Janine N, Girton Jack, Johansen Jørgen, Johansen Kristen M
Abstract excerpt
The JIL-1 kinase localizes to interband regions of Drosophila polytene chromosomes and phosphorylates histone H3 Ser10. Analysis of JIL-1 hypomorphic alleles demonstrated that reduced levels of JIL-1 protein lead to global changes in polytene chromatin structure. Here we have performed a detailed ultrastructural and cytological analysis of the defects in JIL-1 mutant chromosomes. We show that all autosomes and...
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