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Article

Extending MeCP2 interactome: canonical nucleosomal histones interact with MeCP2.

Nucleic acids research - 24 Apr 2024

Ortega-Alarcon David, Claveria-Gimeno Rafael, Vega Sonia, Kalani Ladan, Jorge-Torres Olga C, Esteller Manel, Ausio Juan, Abian Olga, Velazquez-Campoy Adrian

Abstract excerpt

MeCP2 is a general regulator of transcription involved in the repression/activation of genes depending on the local epigenetic context. It acts as a chromatin regulator and binds with exquisite specificity to gene promoters. The set of epigenetic marks recognized by MeCP2 has been already established (mainly, cytosine modifications in CpG and CpA), as well as many of the constituents of its interactome. We unveil...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38321951
DOI: 10.1093/nar/gkae051
PMCID: PMC11039998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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