Article
A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome.
Fertility and sterility - 1 May 2008
Lee Eung-Ji, Oh Bermseok, Lee Jong-Young, Kimm Kuchan, Lee Sook-Hwan, Baek Kwang-Hyun
Abstract excerpt
OBJECTIVE: To investigate several single nucleotide polymorphisms (SNPs) in the insulin receptor (INSR) gene that have significant associations with pathogenesis of polycystic ovary syndrome (PCOS) in a Korean population. DESIGN: Case-control study. SETTING: University-based hospital. PATIENT(S): 134 patients with PCOS and 100 healthy women as controls. INTERVENTION(S): All exons of INSR in DNA samples from 100...
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