Article
A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS.
Molecular human reproduction - 1 Mar 2006
Jin Li, Zhu Xiao-Ming, Luo Qiong, Qian Yuli, Jin Fan, Huang He-Feng
Abstract excerpt
To investigate the association of single-nucleotide polymorphisms (SNPs) in exon 17 of the insulin receptor (INSR) gene with insulin resistance and INSR beta-subunit expression in polycystic ovary syndrome (PCOS) patients, a case-control study was carried out in an academic endocrinology clinic of China. One hundred and nine Chinese patients with PCOS and 107 healthy Chinese women as control were recruited. Their...
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