Article
Association of GWAS identified INSR variants (rs2059807 & rs1799817) with polycystic ovarian syndrome in Indian women.
International journal of biological macromolecules - 1 Feb 2020
Dakshinamoorthy J, Jain Pritesh R, Ramamoorthy Thilagavathi, Ayyappan Rajapriya, Balasundaram Usha
Abstract excerpt
Polycystic ovary syndrome (PCOS), a gynaecological endocrine disorder affects 9% of Indian women and is linked to type II diabetes. The association of INSR (INSulin Receptor gene) variants (rs2059807 and rs1799817) with PCOS was established through genome-wide association studies, yet requires validation for the Indian population. This case-control study included 253 PCOS women and 308 age-matched control. The...
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