Article
[Association between single nucleotide polymorphism of rs2252673 of INSR gene and polycystic ovarian syndrome].
Zhonghua fu chan ke za zhi - 1 Dec 2014
Du Jing, Wang Ze, Zhang Jiangtao, Jia Lili, Zhang Fengli, Shi Yuhua, Chen Zijiang
Abstract excerpt
OBJECTIVE: This study is designed to determine whether an association exists between single nucleotide polymorphism (SNP) variant rs2252673 of insulin receptor (INSR) gene and polycystic ovarian syndrome (PCOS) in Han Chinese in order to identify INSR as a genetic susceptibility factor for PCOS. METHODS: A total of 224 women with PCOS, 192 controls and 672 participants consisting of 224 trios (mother, father and...
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