Article
Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome.
European journal of endocrinology - 1 May 2009
Mukherjee Srabani, Shaikh Nuzhat, Khavale Sushma, Shinde Gayatri, Meherji Pervin, Shah Nalini, Maitra Anurupa
Abstract excerpt
OBJECTIVE: Polycystic ovary syndrome (PCOS) is a multigenic disorder, and insulin resistance is one of its hallmark features. Polymorphisms in exon 17 of insulin receptor (INSR) gene are reported to be associated with PCOS. We investigated this association in Indian women and its putative relatio...
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