Article
Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population.
Stroke - 1 Aug 2005
Nilsson-Ardnor Sofie, Wiklund Per-Gunnar, Lindgren Petter, Nilsson Anna Karin, Janunger Tomas, Escher Stefan A, Hallbeck Björn, Stegmayr Birgitta, Asplund Kjell, Holmberg Dan
Abstract excerpt
BACKGROUND AND PURPOSE: Recent Icelandic studies have demonstrated linkage for common forms of stroke to chromosome 5q12 and association between phosphodiesterase4D (PDE4D) and ischemic stroke. Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Sweden. METHODS: A total of 56 families with 117 affected individuals were included in the linkage...
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