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Article

GSTM1 and codon 72 P53 polymorphism in multiple myeloma.

Annals of hematology - 1 Nov 2007

Ortega Manoela M, Honma Helen N, Zambon Lair, Lorand-Metze Irene, Costa Fernando F, De Souza Carmino A, Lima Carmen S P

Abstract excerpt

The GSTM1 and GSTT1 genes reduce the effects of exposure to cytotoxic agents. Both genes have a null variant allele in which the entire gene is absent. On the other hand, a common polymorphism of the tumour suppressor P53 gene results in either arginine (A) or proline (P) at amino-acid position 72. The A and P alleles code proteins with distinct functions in apoptosis and DNA repair and have been associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17653713
DOI: 10.1007/s00277-007-0347-x

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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