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Article

Influence of p53 codon 72 exon 4, GSTM1, GSTT1 and GSTP1*B polymorphisms in lung cancer risk in a Brazilian population.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2008

Honma Helen N, De Capitani Eduardo M, Perroud Maurício W, Barbeiro Aristóteles S, Toro Ivan F C, Costa Daniel B, Lima Carmen S P, Zambon Lair

Abstract excerpt

PURPOSE: Glutathione S-transferases (GST) modulates the effects of various cytotoxic and genotoxic agents, particularly those derived from benzo[a]pyrene, which is one of the main tobacco carcinogens. Both the mu 1 (GSTM1) and theta 1 (GSTT1) genes have a null variant allele in which the entire g...

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Identifiers

PMID: 18280004
DOI: 10.1016/j.lungcan.2007.12.014

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18280004-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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