Article
Glutathione S-transferase P1 mRNA expression in plasma cell disorders and its correlation with polymorphic variants and clinical outcome.
Cancer epidemiology - 1 Oct 2013
Stella Flavia, Weich Natalia, Panero Julieta, Fantl Dorotea Beatriz, Schutz Natalia, Fundia Ariela F, Slavutsky Irma
Abstract excerpt
BACKGROUND: Glutathione S-transferase P1 (GSTP1) is an important phase II enzyme involved in detoxification of carcinogens. GSTP1 gene overexpression has been observed in a variety of human cancers but there are no studies in plasma cell disorders. The aim of this study was to examine GSTP1 mRNA expression level in multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS). In addition,...
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