Article
No Evidence of Correlation between p53 Codon 72 Polymorphism and Risk of Bladder or Breast Carcinoma in Tunisian Patients
1 Dec 2003
Abstract excerpt
The TP53 gene, frequently mutated in human cancers, carries several polymorphisms. The one most informative and studied concerns codon 72; a single base changes the CGC (arginine) to CCC (proline). The arginine form was considered to be a significant risk factor in the development of cancer. However, various reports on this polymorphism are controversial. We carried out the same investigation in two groups of...
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