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Article

Olanzapine induces SREBP-1-related adipogenesis in 3T3-L1 cells.

Pharmacological research - 1 Sept 2007

Yang Li-Hung, Chen Tzer-Ming, Yu Sung-Tsai, Chen Yen-Hui

Abstract excerpt

Olanzapine is a second-generation atypical antipsychotic drug (AAPD). Major side effects of olanzapine are weight gain and development of diabetes mellitus, which are risk factors of cardiovascular diseases. The possible causes of metabolic adverse effects are known as poor satiety and increased food intake due to blockade of receptors such as 5-HT(2C) in CNS. In this study, we examine the effect of olanzapine on...

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Source

Identifiers

PMID: 17651982
DOI: 10.1016/j.phrs.2007.05.007

Genes

EBP
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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