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Article

Weight Gain and Metabolic Changes During Treatment with Antipsychotics and Antidepressants.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2015

Himmerich Hubertus, Minkwitz Juliane, Kirkby Kenneth C

Abstract excerpt

Weight gain and metabolic disturbances are common side effects during psychopharmacological treatment with specific antipsychotics and antidepressants. The antipsychotics clozapine and olanzapine, and antidepressants tricyclics and mirtazapine have a high risk of inducing weight gain. Recently discovered pathophysiological mechanisms include antihistaminergic effects, activation of hypothalamic adenosine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26100432
DOI: 10.2174/1871530315666150623092031

Genes

CNR1
NPY
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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