Article
An investigation of the 5-HT2C receptor gene as a migraine candidate gene.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Feb 2003
Johnson Matthew P, Lea Rod A, Curtain Robert P, MacMillan John C, Griffiths Lyn R
Abstract excerpt
Migraine is a common complex disorder, currently classified into two main subtypes, migraine with aura (MA) and migraine without aura (MO). The strong preponderance of females to males suggests an X-linked genetic component. Recent studies have identified an X chromosomal susceptibility region (Xq24-q28) in two typical migraine pedigrees. This region harbours a potential candidate gene for the disorder, the...
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