Article
MglA regulates Francisella tularensis subsp. novicida (Francisella novicida) response to starvation and oxidative stress.
Journal of bacteriology - 1 Sept 2007
Guina Tina, Radulovic Dragan, Bahrami Arya J, Bolton Diana L, Rohmer Laurence, Jones-Isaac Kendan A, Chen Jinzy, Gallagher Larry A, Gallis Byron, Ryu Soyoung, Taylor Greg K, Brittnacher Mitchell J, Manoil Colin, Goodlett David R
Abstract excerpt
MglA is a transcriptional regulator of genes that contribute to the virulence of Francisella tularensis, a highly infectious pathogen and the causative agent of tularemia. This study used a label-free shotgun proteomics method to determine the F. tularensis subsp. novicida (F. novicida) proteins that are regulated by MglA. The differences in relative protein amounts between wild-type F. novicida and the mglA...
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