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Article

MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival.

Proceedings of the National Academy of Sciences of the United States of America - 23 Mar 2004

Lauriano Crystal M, Barker Jeffrey R, Yoon Sang-Sun, Nano Francis E, Arulanandam Bernard P, Hassett Daniel J, Klose Karl E

Abstract excerpt

Francisella tularensis is able to survive and grow within macrophages, a trait that contributes to pathogenesis. Several genes have been identified that are important for intramacrophage survival, including mglA and iglC. F. tularensis is also able to survive within amoebae. It is shown here that F. tularensis mglA and iglC mutant strains are not only defective for survival and replication within the...

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Identifiers

PMID: 15010524
DOI: 10.1073/pnas.0307690101
PMCID: PMC384726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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