Article
Microarray analysis of gene expression with age in individual nematodes.
Aging cell - 1 Jun 2004
Golden Tamara R, Melov Simon
Abstract excerpt
We compare the aging of wild-type and long-lived C. elegans by gene expression profiling of individual nematodes. Using a custom cDNA array, we have characterized the gene expression of 4-5 individuals at 4 distinct ages throughout the adult lifespan of wild-type N2 nematodes, and at the same ages for individuals of the long-lived strain daf-2(e1370). Using statistical tools developed for microarray data...
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