Article
The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B.
Acta crystallographica. Section D, Biological crystallography - 1 Aug 2007
Letts James A, Persson Mattias, Schuman Brock, Borisova Svetlana N, Palcic Monica M, Evans Stephen V
Abstract excerpt
The human ABO(H) blood-group antigens are oligosaccharide structures that are expressed on erythrocyte and other cell surfaces. The terminal carbohydrate residue differs between the blood types and determines the immune reactivity of this antigen. Individuals with blood type A have a terminal N-acetylgalactosamine residue and those with blood type B have a terminal galactose residue. The attachment of these...
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