The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

doi:10.1016/0896-6273(91)90334-v

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Article

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

Neuron - 1 Dec 1991

Thor S, Ericson J, Brännström T, Edlund T

Abstract excerpt

We have used immunocytochemical methods to localize the homeodomain LIM protein Isl-1 in the adult rat. Isl-1 immunoreactivity is expressed in polypeptide hormone-producing cells of the endocrine system, in neurons of the peripheral nervous system, and in a subset of brain nuclei. Isl-1 is also expressed in a subset of motoneurons in the spinal cord and brain stem, but not in regions of the central nervous system...

Topics

Animals
DNA-Binding Proteins
Endocrine Glands
Gene Expression
Homeodomain Proteins
Immune Sera
Immunohistochemistry
Islets of Langerhans
LIM-Homeodomain Proteins
Motor Neurons
Nerve Tissue Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurons

Organ Specificity

Phenotype

Pituitary Gland, Anterior

RNA, Messenger

Rats

Rats, Inbred Strains

Source

Open in PubMed

Identifiers

PMID: 1764243
DOI: 10.1016/0896-6273(91)90334-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1764243-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.PMID 1764243Read ↗

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