Article
Characterization of the Caenorhabditis elegans Islet LIM-homeodomain ortholog, lim-7.
FEBS letters - 22 Jan 2009
Voutev Roumen, Keating Ryan, Hubbard E Jane Albert, Vallier Laura G
Abstract excerpt
lim-7 is one of seven Caenorhabditis elegans LIM-homeodomain (LIM-HD)-encoding genes and the sole Islet ortholog. LIM-HD transcription factors, including Islets, function in neuronal and non-neuronal development across diverse phyla. Our results show that a lim-7 deletion allele causes early larval lethality with terminal phenotypes including uncoordination, detached pharynx, constipation and morphological...
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