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Article

The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities.

Molecular biology of the cell - 1 Apr 2005

Hao Aijun, Novotny-Diermayr Veronica, Bian Wei, Lin Baohong, Lim Cheh Peng, Jing Naihe, Cao Xinmin

Abstract excerpt

Islet1 (Isl1) belongs to the LIM homeodomain transcription factor family. Its roles in differentiation of motor neurons and organogenesis of pancreas and heart have been revealed. However, less is known about its regulatory mechanism and the target genes. In this study, we identified interactions between Isl1 and Janus tyrosine kinase (JAK), as well as signal transducer and activator of transcription (Stat)3, but...

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Identifiers

PMID: 15659653
DOI: 10.1091/mbc.e04-08-0664
PMCID: PMC1073642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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