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Article

Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jul 2007

Higashimoto Ken, Kuhn Peter, Desai Dhaval, Cheng Xiaodong, Xu Wei

Abstract excerpt

Multiple protein arginine methyltransferases are involved in transcriptional activation of nuclear receptors. Coactivator-associated arginine methyltransferase 1 (CARM1)-mediated histone methylation has been shown to activate nuclear receptor-dependent transcription; however, little is known about the regulation of its enzymatic activity. Here, we report that the methyltransferase activity of CARM1 is negatively...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17640894
DOI: 10.1073/pnas.0610792104
PMCID: PMC1941467

Genes

CARM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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