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Article

Automethylation of CARM1 allows coupling of transcription and mRNA splicing.

Nucleic acids research - 1 Apr 2011

Kuhn Peter, Chumanov Rob, Wang Yidan, Ge Ying, Burgess Richard R, Xu Wei

Abstract excerpt

Coactivator-associated arginine methyltransferase 1 (CARM1), the histone arginine methyltransferase and coactivator for many transcription factors, is subject to multiple post-translational modifications (PTMs). To unbiasedly investigate novel CARM1 PTMs we employed high-resolution top-down mass spectrometry. Surprisingly, mouse CARM1 expressed in insect and mammalian expression systems was completely...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21138967
DOI: 10.1093/nar/gkq1246
PMCID: PMC3074151

Genes

CARM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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