Article
HIV-1 coreceptor usage determination in clinical isolates using clonal and population-based genotypic and phenotypic assays.
Journal of virological methods - 1 Dec 2007
Van Baelen Kurt, Vandenbroucke Ina, Rondelez Evelien, Van Eygen Veerle, Vermeiren Hans, Stuyver Lieven J
Abstract excerpt
Orally bioavailable CXCR4 and CCR5 coreceptor antagonists are being developed for the treatment of HIV-1 infection. A new tropism-testing platform, which offers various options depending on the needs, was established. Each option has specific characteristics in terms of sensitivity, information,...
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