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Article

Mechanistic role of a disease-associated genetic variant within the ADAM33 asthma susceptibility gene.

BMC medical genetics - 17 Jul 2007

Del Mastro Richard G, Turenne Laura, Giese Heidi, Keith Tim P, Van Eerdewegh Paul, May Klaus J W, Little Randall D

Abstract excerpt

BACKGROUND: ADAM33 has been identified as an asthma-associated gene in an out-bred population. Genetic studies suggested that the functional role of this metalloprotease was in airway remodeling. However, the mechanistic roles of the disease-associated SNPs have yet to be elucidated especially in...

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Identifiers

PMID: 17640346
DOI: 10.1186/1471-2350-8-46
PMCID: PMC1955437

Genes

ADAM33

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17640346-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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