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Article

Tumor immunity and autoimmunity induced by immunization with homologous DNA.

15 Sept 1998

Abstract excerpt

The immune system can recognize self antigens expressed by cancer cells. Differentiation antigens are prototypes of these self antigens, being expressed by cancer cells and their normal cell counterparts. The tyrosinase family proteins are well characterized differentiation antigens recognized by antibodies and T cells of patients with melanoma. However, immune tolerance may prevent immunity directed against...

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Identifiers

PMID: 9739060
DOI: 10.1172/jci4004

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