Article
Mitochondrial and energetic cardiac phenotype in hypothyroid rat. Relevance to heart failure.
Pflugers Archiv : European journal of physiology - 1 Dec 2007
Athéa Yoni, Garnier Anne, Fortin Dominique, Bahi Lahoucine, Veksler Vladimir, Ventura-Clapier Renée
Abstract excerpt
Changes in thyroid status are associated with profound alterations in biochemical and physiological functioning of cardiac muscle, although its impact on cardiac energy metabolism is still debated. Similarities between the changes in cardiac gene expression in pathological hypertrophy leading to heart failure and hypothyroidism prompted scientists to suggest a role for thyroid hormone status in the development of...
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