Article
Functional and metabolic adaptation of the heart to prolonged thyroid hormone treatment.
American journal of physiology. Heart and circulatory physiology - 1 Jan 2003
Degens H, Gilde A J, Lindhout M, Willemsen P H M, Van Der Vusse G J, Van Bilsen M
Abstract excerpt
In heart failure, thyroid hormone (TH) treatment improves cardiac performance. The long-term effects of TH on cardiac function and metabolism, however, are incompletely known. To investigate the effects of up to 28 days of TH treatment, male Wistar rats received 3,3',5-triiodo-l-thyronine (200 microg/kg sc per day) leading to a 2.5-fold rise in plasma fatty acid (FA) level and progressive cardiac hypertrophy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.