Article
Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia.
Thyroid : official journal of the American Thyroid Association - 1 Aug 2020
Herrmann Beate, Harder Lisbeth, Oelkrug Rebecca, Chen Jiesi, Gachkar Sogol, Nock Sebastian, Resch Julia, Korkowski Markus, Heuer Heike, Mittag Jens
Abstract excerpt
Background: Tachycardia, cardiac hypertrophy, and elevated body temperature are major signs of systemic hyperthyroidism, which are considered to reflect the excessive thyroid hormone (TH) action in the respective peripheral tissues. However, recent observations indicate that the central actions of TH also contribute substantially to cardiovascular regulation and thermogenesis. Methods: In this study, we dissect...
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