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Article

Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.

Obesity (Silver Spring, Md.) - 1 Jul 2007

Warensjö Eva, Ingelsson Erik, Lundmark Per, Lannfelt Lars, Syvänen Ann-Christine, Vessby Bengt, Risérus Ulf

Abstract excerpt

OBJECTIVE: Obesity and insulin resistance are major risk factors for metabolic diseases and are influenced by lifestyle and genetics. The lipogenic enzyme, stearoyl-coenzyme A-desaturase (SCD), is related to obesity. Further, SCD1-deficent mice are protected against obesity and insulin resistance...

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Identifiers

PMID: 17636091
DOI: 10.1038/oby.2007.206

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17636091-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.PMID 17636091Read ↗

Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: a prospective study.Semantic proximity Read ↗

Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study.Semantic proximity Read ↗

Polymorphisms rs2167444 and rs508384 in the SCD1 Gene Are Linked with High ApoB-48 Levels and Adverse Profile of Cardiometabolic Risk Factors.Semantic proximity Read ↗

The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population.Semantic proximity Read ↗

Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.Semantic proximity Read ↗

Variants in the CD36 gene locus determine whole-body adiposity, but have no independent effect on insulin sensitivity.Semantic proximity Read ↗

C allele of SCD1 rs7849 (T/C) polymorphism and Susceptibility to Type 2 Diabetes: A pilot study from BangladeshSemantic proximity Read ↗

Genetic variation in stearoyl-CoA desaturase 1 is associated with metabolic syndrome prevalence in Costa Rican adults.Semantic proximity Read ↗

Influence of Fatty Acid Desaturase Enzyme-1 Gene (FADS-1) Polymorphism on Serum Polyunsaturated Fatty Acids Levels, Desaturase Enzymes, Lipid Profile, and Glycemic Control Parameters in Newly Diagnosed Diabetic Mellitus PatientsSemantic proximity Read ↗

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.Semantic proximity Read ↗

A Single Nucleotide Polymorphism (rs3811792) Affecting Human SCD5 Promoter Activity Is Associated with Diabetes Mellitus.Semantic proximity Read ↗

Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation.Semantic proximity Read ↗

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