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Article

Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.

Obesity (Silver Spring, Md.) - 1 Jul 2007

Warensjö Eva, Ingelsson Erik, Lundmark Per, Lannfelt Lars, Syvänen Ann-Christine, Vessby Bengt, Risérus Ulf

Abstract excerpt

OBJECTIVE: Obesity and insulin resistance are major risk factors for metabolic diseases and are influenced by lifestyle and genetics. The lipogenic enzyme, stearoyl-coenzyme A-desaturase (SCD), is related to obesity. Further, SCD1-deficent mice are protected against obesity and insulin resistance. We hypothesized that genetic polymorphisms in the SCD1 gene would be associated with obesity, insulin sensitivity,...

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Source

Identifiers

PMID: 17636091
DOI: 10.1038/oby.2007.206

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.PMID 17636091Read ↗

Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: a prospective study.Semantic proximity Read ↗

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Polymorphisms rs2167444 and rs508384 in the SCD1 Gene Are Linked with High ApoB-48 Levels and Adverse Profile of Cardiometabolic Risk Factors.Semantic proximity Read ↗

The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population.Semantic proximity Read ↗

Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.Semantic proximity Read ↗

Variants in the CD36 gene locus determine whole-body adiposity, but have no independent effect on insulin sensitivity.Semantic proximity Read ↗

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Genetic variation in stearoyl-CoA desaturase 1 is associated with metabolic syndrome prevalence in Costa Rican adults.Semantic proximity Read ↗

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A Single Nucleotide Polymorphism (rs3811792) Affecting Human SCD5 Promoter Activity Is Associated with Diabetes Mellitus.Semantic proximity Read ↗

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