Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.

Diabetologia - 1 Nov 2006

Harding A-H, Loos R J F, Luan J, O'Rahilly S, Wareham N J, Barroso I

Abstract excerpt

AIMS/HYPOTHESIS: The sterol regulatory element-binding factor (SREBF)-1c is a transcription factor involved in the regulation of lipid and glucose metabolism. We have previously found evidence that a common SREBF1c single-nucleotide polymorphism (SNP), located between exons 18c and 19c, is associ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Blood Glucose
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Diabetes Mellitus, Type 2

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Share to Sterol Regulatory Element Binding Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 17019602
DOI: 10.1007/s00125-006-0430-1
PMCID: PMC2668914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17019602-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes.PMID 17019602Read ↗

Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.Semantic proximity Read ↗

The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population.Semantic proximity Read ↗

Association of sterol regulatory element-binding protein-1c gene polymorphism with type 2 diabetes mellitus, insulin resistance and blood lipid levels in Chinese population.Semantic proximity Read ↗

SREBF-1 Gene Polymorphisms Are Associated With Obesity and Type 2 Diabetes in French Obese and Diabetic CohortsSemantic proximity Read ↗

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1.Semantic proximity Read ↗

Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism.Semantic proximity Read ↗

Association study of SREBF-2 gene polymorphisms and the risk of type 2 diabetes in a sample of Iranian population.Semantic proximity Read ↗

Influence of Fatty Acid Desaturase Enzyme-1 Gene (FADS-1) Polymorphism on Serum Polyunsaturated Fatty Acids Levels, Desaturase Enzymes, Lipid Profile, and Glycemic Control Parameters in Newly Diagnosed Diabetic Mellitus PatientsSemantic proximity Read ↗

A Single Nucleotide Polymorphism (rs3811792) Affecting Human SCD5 Promoter Activity Is Associated with Diabetes Mellitus.Semantic proximity Read ↗

Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.Semantic proximity Read ↗

Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.Semantic proximity Read ↗

The rs2341471-G/G genotype of activating transcription factor 6 (ATF6) is the risk factor of type 2 diabetes in subjects with obesity or overweight.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.