Article
The SREBF-1 locus is associated with type 2 diabetes and plasma adiponectin levels in a middle-aged Austrian population.
International journal of obesity (2005) - 1 Jul 2007
Felder T K, Oberkofler H, Weitgasser R, Mackevics V, Krempler F, Paulweber B, Patsch W
Abstract excerpt
CONTEXT: The sterol regulatory element-binding protein-1c (SREBP-1c) is a transcription factor involved in the regulation of lipid and glucose metabolism and has been implicated in the pathophysiology of type 2 diabetes mellitus (T2DM). OBJECTIVE: We aimed to confirm associations of the SREBF-1 gene with T2DM in an Austrian population and to study possible associations with diabetes-related quantitative traits....
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