Article
Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study.
PloS one - 1 Jan 2012
Arregui Maria, Buijsse Brian, Stefan Norbert, Corella Dolores, Fisher Eva, di Giuseppe Romina, Coltell Oscar, Knüppel Sven, Aleksandrova Krasimira, Joost Hans-Georg, Boeing Heiner, Weikert Cornelia
Abstract excerpt
BACKGROUND: Stearoyl-CoA desaturase-1 (SCD1) is an enzyme involved in lipid metabolism. In mice and humans its activity has been associated with traits of the metabolic syndrome, but also with the prevention of saturated fatty acids accumulation and subsequent inflammation, whereas for liver fat content inconsistent results have been reported. Thus, variants of the gene encoding SCD1 (SCD1) could potentially...
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