Article
Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: a prospective study.
Molecular nutrition & food research - 1 Dec 2013
Martín-Núñez Gracia María, Cabrera-Mulero Rebeca, Rojo-Martínez Gemma, Gómez-Zumaquero Juan Miguel, Chaves Felipe Javier, de Marco Griselda, Soriguer Federico, Castaño Luis, Morcillo Sonsoles
Abstract excerpt
SCOPE: The serum fatty acid (FA) composition is influenced by dietary fat and the endogenous production of FAs. Stearoyl CoA desaturase 1 (SCD1) is the rate-limiting enzyme catalyzing the synthesis of MUFAs from saturated FAs. Variations in SCD1 activity have been associated with obesity, diabetes, or inflammation. We evaluated the associations between genetic variation of the SCD1 gene, SCD1 activity, intake of...
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