Article
Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: a prospective study.
Molecular nutrition & food research - 1 Dec 2013
Martín-Núñez Gracia María, Cabrera-Mulero Rebeca, Rojo-Martínez Gemma, Gómez-Zumaquero Juan Miguel, Chaves Felipe Javier, de Marco Griselda, Soriguer Federico, Castaño Luis, Morcillo Sonsoles
Abstract excerpt
SCOPE: The serum fatty acid (FA) composition is influenced by dietary fat and the endogenous production of FAs. Stearoyl CoA desaturase 1 (SCD1) is the rate-limiting enzyme catalyzing the synthesis of MUFAs from saturated FAs. Variations in SCD1 activity have been associated with obesity, diabete...
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