Article
Variants in the CD36 gene locus determine whole-body adiposity, but have no independent effect on insulin sensitivity.
Obesity (Silver Spring, Md.) - 1 May 2011
Heni Martin, Müssig Karsten, Machicao Fausto, Machann Jürgen, Schick Fritz, Claussen Claus D, Stefan Norbert, Fritsche Andreas, Häring Hans-Ulrich, Staiger Harald
Abstract excerpt
CD36 variants have been associated with type 2 diabetes, features of the metabolic syndrome, and alterations in lipid metabolism. In contrast, the effect of single-nucleotide polymorphisms (SNPs) in CD36 on insulin resistance is controversial in literature. Therefore, we investigated whether genetic variation within the CD36 gene locus affects insulin resistance in a well-phenotyped cohort of white European...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
